全文获取类型
| 收费全文 | 738篇 |
| 免费 | 55篇 |
| 国内免费 | 15篇 |
专业分类
| 耳鼻咽喉 | 3篇 |
| 妇产科学 | 3篇 |
| 基础医学 | 27篇 |
| 口腔科学 | 14篇 |
| 临床医学 | 18篇 |
| 内科学 | 48篇 |
| 皮肤病学 | 2篇 |
| 神经病学 | 4篇 |
| 特种医学 | 7篇 |
| 外科学 | 67篇 |
| 综合类 | 202篇 |
| 预防医学 | 11篇 |
| 眼科学 | 12篇 |
| 药学 | 54篇 |
| 中国医学 | 323篇 |
| 肿瘤学 | 13篇 |
出版年
| 2024年 | 1篇 |
| 2023年 | 10篇 |
| 2022年 | 28篇 |
| 2021年 | 27篇 |
| 2020年 | 25篇 |
| 2019年 | 70篇 |
| 2018年 | 63篇 |
| 2017年 | 52篇 |
| 2016年 | 27篇 |
| 2015年 | 20篇 |
| 2014年 | 41篇 |
| 2013年 | 35篇 |
| 2012年 | 27篇 |
| 2011年 | 45篇 |
| 2010年 | 37篇 |
| 2009年 | 18篇 |
| 2008年 | 24篇 |
| 2007年 | 30篇 |
| 2006年 | 21篇 |
| 2005年 | 14篇 |
| 2004年 | 19篇 |
| 2003年 | 15篇 |
| 2002年 | 24篇 |
| 2001年 | 21篇 |
| 2000年 | 17篇 |
| 1999年 | 8篇 |
| 1998年 | 11篇 |
| 1997年 | 11篇 |
| 1996年 | 3篇 |
| 1995年 | 4篇 |
| 1994年 | 6篇 |
| 1992年 | 6篇 |
| 1991年 | 9篇 |
| 1990年 | 3篇 |
| 1989年 | 3篇 |
| 1988年 | 3篇 |
| 1987年 | 1篇 |
| 1986年 | 2篇 |
| 1985年 | 7篇 |
| 1984年 | 5篇 |
| 1983年 | 3篇 |
| 1982年 | 4篇 |
| 1980年 | 2篇 |
| 1979年 | 2篇 |
| 1977年 | 1篇 |
| 1974年 | 2篇 |
| 1973年 | 1篇 |
排序方式： 共有808条查询结果，搜索用时 46 毫秒
11.
陈亦人教授运用芍药甘草汤的经验 总被引：4，自引：0，他引：4
芍药甘草汤具有养阴血、柔筋脉、舒挛缓急的功效，主治筋脉挛急之证。介绍陈亦人教授运用芍药甘草汤的经验，并附验案分析。 相似文献
12.
13.
Lei ZHU Zhi Jun ZHAO Xiao Bin REN Qiang LI Hua DING Zhou SUN Qing Jun KAO Li Hua WANG 《Biomedical and environmental sciences : BES》2018,31(1):76-80
正The molecular pathogenesis of T-2toxin-induced cartilage destruction has not been fully unraveled yet.The aim of this study was to detect changes in serum metabolites in a rat anomaly model with articular cartilage destruction.Thirty healthy male Wistar rats were fed a diet containing T-2 toxin(300 ng/kg chow)for 3 months. 相似文献
14.
陈宪海教授根据外感病的临床传变特点,结合外感肺病的病机以及病情演变规律,联系整体观念以及脏腑相关理论,认为外感肺病在临床辨证治疗中应注重层次性,即外围层次、本脏层次、子母层次。在不同层次给予不同治疗,在表者宜解表驱邪,方以参苏饮加减;在肺者清肃肺气,方以三拗汤加减;及脾者宜健脾化痰,方以四君子汤加减。各层次治疗重点不同,选方用药精良,临床随症灵活加减,恢复肺之宣降功能,临床疗效较好。 相似文献
15.
Background
People with prehypertension are highly likely to develop hypertension and other cardiovascular diseases. Lifestyle modifications may prevent hypertension in patients with prehypertension, but evidence remains scarce in developing countries. This study aimed to investigate whether a community-based intervention could prevent hypertension through lifestyle modifications in people with prehypertension in the rural areas of China.Methods
A community-based quasi-experiment design was applied. Eighteen villages from six townships in Sheyang county, a rural area in eastern China, were randomly sampled. Of these local residents, patients with prehypertension—a systolic blood pressure (SBP) of 120–139 mm Hg or a diastolic blood pressure (DBP) of 80–89 mm Hg—and who were 30–60 years old were screened. Participants from three of the townships (n=206) were randomly assigned to the intervention group, and those from the other three townships (n=250) were assigned to the control group. At the outset, intervention group participants received individual consultations from a community health management team to assess their self-management ability, determine their lifestyle, set goals for a healthier lifestyle, and design individualised action plans. A guideline booklet was provided to intervention group participants, which contained detailed explanations of hypertension, prehypertension, healthy lifestyles and their impacts, and methods to lose weight, cease smoking, and deal with mental pressure. Intervention group participants also received quarterly follow-ups to assess the implementation of action plans, identify difficulties in changing unhealthy lifestyles, and find feasible solutions. In both intervention and control groups, usual care was provided to participants according to national guidelines, and the available resources were the same across the townships. Evaluations were conducted at baseline, and at the end of months 6, 12, 18, and 30. Between-group analyses were performed using repeated measures ANOVA. Written informed consent was obtained from the participants.Findings
At 30 months, 18 participants in the intervention group (n=188) showed progression to hypertension, whereas 47 in the control group (n=234) developed hypertension. This difference between intervention and control groups was statistically significant (9·6 vs 20·1%, p=0·007). Significant changes in DBP (–2·7 vs 0·7 mmHg, p<0·0001), weight (–0·79 vs ?0·66 kg, p=0·029), and daily walking steps (11?500 vs 8000 steps, p<0·0001) were observed between intervention and control groups. No differential effects were found for SBP, drinking, and smoking, with both groups showing substantial improvements.Interpretation
This intervention could prevent hypertension among patients with prehypertension by improving health-related behaviours. This study might be one of the first community-based experiments implemented among people with prehypertension in the rural areas of China. Further investigations are required to assess the sustainability of this intervention.Funding
This study was funded by the Postgraduates Innovation Project of Jiangsu Province (KYZZ15_0267). 相似文献16.
介绍陈定潜主任医师治疗内科病症的经验,重视湿毒致病,提倡缓图法及分阶段治疗,强调用药须注重保护胃气。 相似文献
17.
郑莲莲 《浙江中西医结合杂志》2015,25(8)
目的 探讨双歧三联活菌胶囊联合降脂化浊汤对非酒精性脂肪性肝炎患者肠黏膜屏障的保护作用。方法 选取门诊治疗的NASH患者90例,随机分为中西医组(n=45例)和西医组(n=45例)。西医组患者予以双歧三联活菌胶囊630mg/次,2次/d,温水口服;中西医组患者在西医组治疗基础上予以疏肝降脂汤,加水煎煮至200ml,分早晚两次口服,两组均连用12周。检测并比较两组患者治疗前后肝功能指标、血清内毒素、D-乳酸和二胺氧化酶(DAO)水平的变化。结果 治疗12周后,两组ALT、AST和γ-GT以及血清内毒素、D-乳酸和DAO水平较前均明显下降(P<0.05或P<0.01),且中西医组下降值较西医组更明显(P<0.05)。结论 双歧三联活菌胶囊联合疏肝降脂汤治疗NASH的疗效较显著,能降低血清内毒素、D-乳酸和DAO水平,减少或抑制内毒素血症产生,降低肠黏膜通透性,修复受损肠粘膜屏障,使得肝功能逐渐恢复正常。 相似文献
18.
从五运六气理论推演天时气化,据实际气候指标拟定全国16方域六气气化数值。参合两者,提示本次新型冠状病毒何以发于己亥岁末之鄂,并据患者易见症状表现,辨识此肺炎乃风温夹湿之疫厉。然后分析其易感之地,以鄂湘赣为最,次则浙闽两广江苏,以其气化相近也;好发之人,以肺脾气虚湿盛者为甚,次则肝气失调、素体孱弱者,以其正虚邪凑也。进而推测疫情演化趋势,庚子岁半之前,疫情正烈;岁半而后,当衰减而泯灭。中医防治,当以出具防治方药为本,参考古今医家治疫理法,结合自家经验,拟定防治方药八帧。 相似文献
19.
20.
目的研究人参属植物人参Panax ginseng、三七P. notoginseng和西洋参P. quinquefolium高温蒸制前后主要人参皂苷的含量变化,并测定高温蒸制前后样品对4株肿瘤癌细胞的细胞毒活性。方法采用HPLC建立了测定22种皂苷含量的分析方法,测定这些皂苷在人参属植物及其高温蒸制品中的含量。用MTT法测定人参属植物及其高温蒸制品对4株人类癌细胞(人类骨髓癌HL-60细胞、肝癌SMMC-7721细胞、肺癌A-549细胞、乳腺癌SK-BR-3细胞)的细胞毒活性。结果从人参、三七和西洋参及高温蒸制后的样品中鉴定出22个皂苷,包括人参皂苷Rg1、Re、Rb1、Rc、Rb2、Rd、Rk3、Rh4、Rk1、Rg5、Rb3、Rh3、Rk2,20(S)-人参皂苷Rh1、20(R)-人参皂苷Rh1、三七皂苷Fc、三七皂苷R1、绞股蓝皂苷IX、20(S/R)-三七皂苷Ft1、20(S/R)-人参皂苷Rg3、人参皂苷Rs3、人参皂苷Rh2。人参皂苷Rg1、Re、Rb1、Rc、Rb2和Rd为人参的主要成分;人参皂苷Rg1、Re、Rb1和Rd为西洋参的主要成分;人参皂苷Rg1、Re、Rb1、Rd和三七皂苷R1为三七的主要成分,高温蒸制后这3种植物的主要成分全部转化为人参皂苷Rk3、Rh4、Rk1、Rg5和20(S/R)-人参皂苷Rg3,在高温蒸制后的三七中还检测到20(S)-人参皂苷Rh1和20(R)-人参皂苷Rh1。三七皂苷Fc、人参皂苷Rb3和绞股蓝皂苷IX为三七茎叶的主要成分,高温蒸制后转化为另外8个主要成分20(S/R)-三七皂苷Ft1,20(S/R)-人参皂苷Rg3、Rs3、Rk1、Rg5,20(S/R)-人参皂苷Rh2、Rh3和Rk2。细胞毒活性结果显示,高温蒸制三七的细胞毒活性比高温蒸制人参和高温蒸制西洋参强,高温蒸制三七的细胞毒活性比三七的活性强,说明高温蒸制后三七的细胞毒活性增强。结论人参、西洋参和三七经过高温蒸制后原来的主要成分基本消失,随之转化为其他主要成分,高温蒸制三七的细胞毒活性最强。 相似文献